Double down for a double win.
نویسنده
چکیده
The rationale for using multiple inhibitors between and within the phosphoinositide 3-kinase/AKT/mTOR and RAS/MEK/ERK pathways is scientifically compelling, and a limited number of experimental agents are currently being tested in phase I combinations. Patient subpopulations, whose tumors are defined by genetic lesions, are showing promising responses to this approach.
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عنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 18 8 شماره
صفحات -
تاریخ انتشار 2012